Organocatalytic aza-Michael addition represents the conjugate addition of amines or related nitrogen nucleophiles to electron-deficient olefins under the influence of small organic molecules. In ...
In 1887, chemist Sir Arthur Michael reported a nucleophilic addition reaction to the β-position of α,β- unsaturated carbonyl compounds. These reactions, named Michael addition reactions, have been ...
The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...