Before testing new therapies in animals, researchers now have a more efficient starting point—lab-grown canine muscle cells that can help identify what works and what doesn't.

During development, biological tissues acquire their shape and organization by integrating internal and external cues, with mechanics playing a central role. Mechanical forces steer cell behavior and ...

The neuromuscular junction (NMJ) is essential for transmitting signals from motor neurons (MNs) to skeletal muscles (SKMs), and its dysfunction can lead to severe motor disorders. However, our ...

Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.

Skeletal muscle organoids help scientists bypass bottlenecks in satellite cell production for muscle regeneration research. Researchers typically create organoid models for other biological systems ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote ...

Before testing new therapies in animals, researchers now have a more efficient starting point — lab-grown canine muscle cells that can help identify what works and what does not. Developed at the ...