A Korean research team has developed a new viral vector technology that significantly improves the production efficiency of next-generation cell and gene therapies known as CAR immune cell therapies, ...

Signal transduction and gene regulation are at the heart of cell and developmental biology, driving cell fate decisions and tissue homeostasis. In cancer, ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a ...

Researchers relied on a newer gene-editing technique that may make it possible to engineer embryos, a prospect that has long alarmed bioethicists. By Carl Zimmer Scientists at Columbia University have ...

MIT scientists have found a way to make gene editing far safer and more accurate — a breakthrough that could reshape how we treat hundreds of genetic diseases. By fine-tuning the tiny molecular “tools ...

Physician and molecular biologist Katherine High remembers sitting at a staff meeting of the gene therapy company Spark Therapeutics on November 15, 2018, waiting to hear from a guest speaker, when ...

The US Food and Drug Administration on Thursday approved the first gene therapy for inherited hearing loss, a one-time treatment that proved to be life-changing for a small number of children in a ...

An experimental gene therapy appears safe and highly effective for restoring hearing to people born with a rare form of deafness, researchers reported Wednesday. The study, the largest and longest to ...

Researchers at the University of Bayreuth and Forschungszentrum Jülich have demonstrated that specific light-sensitive enzymes – so-called sensor histidine kinases (SHKs) – transmit their signal ...

A person’s genes play a far greater role in likely lifespan than previously thought, according to a major new study published Thursday in the journal Science. Subscribe to read this story ad-free Get ...

In 2018, a nervous-looking He Jiankui took the stage at a scientific conference in Hong Kong. A hush settled over the packed auditorium as the soft-spoken Chinese scientist adjusted his microphone and ...

Mendel’s monastery garden experiments went largely unnoticed during his life, but their implications would ripple through science decades later. Gregor Mendel, Austrian botanist and founder of ...